Open research library

Start with the claim. Follow the source.

Every starter record separates community interest, human-evidence work still needed, safety context, and anti-doping context. It is an editorial queue, not a product catalogue.

9 research records

starter reviewUncertainty is high

BPC-157

Synthetic peptide discussed in injury and recovery communities

tendon and soft-tissue claimsrecovery claims

A 2025 two-participant safety pilot and a 2026 ex-vivo human-tissue experiment do not test tendon healing or recovery. An older planned phase-I registration has no posted results. No community-claim efficacy conclusion is supported by these records.

Open research record
starter reviewTested-sport concern

TB-500

Thymosin beta-4 fragment discussed in tissue-repair communities

tissue-repair claimsrecovery claims

Do not merge TB-500 with full-length thymosin β4. Recent human studies found in this update concern different thymosin β4 molecules/formulations and unrelated eye or early-phase contexts; they are not evidence for TB-500 or recovery claims.

Open research record
starter reviewTested-sport concern

CJC-1295

Growth-hormone-releasing hormone analogue

growth-hormone claimsbody-composition claims

An older randomised study in healthy adults found sustained GH and IGF-I biomarker changes. It did not test muscle gain, fat loss, appearance, performance, recovery, or long-term safety; biomarker change is not a community-claim outcome.

Open research record
starter reviewTested-sport concern

Ipamorelin

Growth-hormone secretagogue

growth-hormone claimsrecovery claims

A phase-II postoperative-ileus study in surgical patients reported no significant difference versus placebo in key or secondary efficacy analyses. It does not test body composition, athletic recovery, or appearance claims.

Open research record
starter reviewTested-sport concern

AOD-9604

Growth-hormone fragment discussed in body-composition communities

fat-loss claimsbody-composition claims

FDA meeting material summarising historical obesity studies states that the clinical studies reviewed did not show statistically significant weight loss versus placebo and notes limited underlying reporting. This does not test recovery or joint claims.

Open research record
starter reviewSafety review needed

Melanotan II

Synthetic peptide discussed in tanning and appearance communities

tanning claimsappearance claims

The direct human paper identified is an early phase-I pilot in three men from 1996. It observed pigmentation and short-term symptoms but is far too small and old to establish safety or a modern appearance-use conclusion.

Open research record
starter reviewFormulation matters

GHK-Cu

Copper peptide discussed in skin and hair communities

skin appearance claimshair-related claims

A 2026 ClinicalTrials.gov record describes a recruiting topical wound-healing study, but has no posted results. A planned topical wound study is not evidence for hair, cosmetic appearance, injectable products, or efficacy.

Open research record
starter reviewCondition-specific evidence

Tesamorelin

Growth-hormone-releasing factor analogue with a specific U.S. labelled indication

body-composition claimsvisceral-fat claimsgrowth-hormone claims

Recent controlled research in people with HIV and metabolic disease found changes in visceral and hepatic fat in that specific clinical population. FDA labelling limits the indication to HIV-associated lipodystrophy and explicitly says it is not for weight-loss management.

Open research record
starter reviewMedical trial context

Retatrutide

Investigational triple hormone-receptor agonist

body-composition claimsweight-loss claimsmetabolic-health claims

A 2026 phase-III study in adults with type-2 diabetes reported body-weight and glycaemic outcomes over 40 weeks. This is clinical evidence in a defined medical population, not an individual recommendation or evidence for general appearance goals.

Open research record

Source register

Where this first dataset comes from

anti-doping

2026 Prohibited List

World Anti-Doping Agency

Refresh: Every annual list, plus WADA updates

Verify the applicable List and any Therapeutic Use Exemption requirements with the athlete's anti-doping organisation.

trial registry

ClinicalTrials.gov API

ClinicalTrials.gov / U.S. National Library of Medicine

Refresh: Weekdays; check dataTimestamp before ingestion

A registered study is not proof of efficacy, safety, completion, or publication.

safety signals

openFDA Drug Adverse Event API

U.S. Food and Drug Administration

Refresh: Quarterly; may lag source data

Reports do not establish causation and cannot estimate event frequency or incidence.

bibliographic index / primary paper links

PubMed

U.S. National Library of Medicine

Refresh: Search on each editorial review; record the search date and exact paper URL

A PubMed record indexes a paper; the study design, population, exact substance, and limits must still be extracted from that paper.

trial registry

ClinicalTrials.gov study records

ClinicalTrials.gov / U.S. National Library of Medicine

Refresh: Recheck status and results before each publication update

A registration is not a result. Study descriptions are supplied by the responsible party; no-result records must never be presented as efficacy or safety evidence.

U.S. product labelling / regulatory

EGRIFTA WR (tesamorelin) prescribing information

U.S. Food and Drug Administration

Refresh: Check Drugs@FDA before each status update

The labelled indication is limited to reduction of excess abdominal fat in adults with HIV-associated lipodystrophy; the label states it is not indicated for weight-loss management.